Size and growth in 33 countries and regions, with clinical trials and research from public sources.
"–" means we have no size for that place yet. 2033 values are projected from the 2023 size and the CAGR. Regions count only the countries we report on for trials.
Purdue Pharma
Teva Pharmaceuticals
Collegium Pharmaceutical
Pfizer
Inspirion Delivery Technologies
Egalet
Acura Pharmaceuticals
PubMed lists about 74 papers on the topic since 2021.
Sources: market size and growth: Acuitas Health Analytics research (2023 base year, forecasts to 2033). Trials: ClinicalTrials.gov. Research: PubMed (US National Library of Medicine). Fetched 10 Nov 2026. Trials and papers are found by search words, so counts are a guide.