OTC & Nutraceuticals

Herbal Supplements: Quality, Safety and Trust

Published 5 min read Acuitas Health Analytics

Herbal Supplements: Quality, Safety and Trust

Herbs such as turmeric, ashwagandha, ginseng and ginger are sold as capsules, powders and teas. Many come from long traditions like Ayurveda and traditional Chinese medicine. Being natural does not always mean being safe or effective.

How widely are they used?

WHO reports that 170 of its 194 member states report the use of traditional medicine. In these countries, 40–90% of people use it [1]. In 2022, WHO set up its Global Centre for Traditional Medicine in India, backed by US$250 million from the Government of India [2].

WHO member states (of 194)170Report traditional medicine use24Did not report
Source: WHO [1].

Quality and safety concerns

  • In the US, the FDA does not review supplements for safety and effectiveness before they are sold [3].
  • Some products have been found to contain hidden prescription drugs, mostly those sold for weight loss, sexual health and bodybuilding [4].
  • Herbs can interact with prescription medicines [3].
  • Some products have been contaminated with heavy metals or the wrong plant [5].

How buyers can choose better

  • Look for third-party quality seals that test what is in the bottle.
  • Tell your doctor and pharmacist about every supplement you take [3].
  • Be wary of claims that a product cures disease.

Go deeper

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Traditional medicine goes global

For many people, traditional medicine is the main source of health care. It is local, affordable and fits their culture [1]. WHO's second Global Summit on traditional medicine, held in New Delhi in December 2025, focused on evidence and safe use [1]. WHO is also building a Traditional Medicine Global Library to gather research in one place [6].

People using traditional medicine in WHO member states that report it (%)40%Lower estimate90%Upper estimate
Source: WHO, Dec 2025 [1]: "40–90% of their populations".

Natural is not the same as safe

The NCCIH warns that herbs carry the same dangers as other active compounds [7]. They can cause side effects, interact with medicines and harm people with some health conditions. Some ashwagandha products, for example, have been linked to rare liver injury [8].

Herb and drug interactions

Many people take herbs alongside prescription medicines without telling their doctor. Some herbs change how the body breaks down drugs. That can make a medicine too strong or too weak. This matters most for blood thinners, heart drugs, HIV medicines, transplant drugs and cancer treatments.

Contamination and mix-ups

The NCCIH reports that some Chinese herbal products have been found contaminated with toxic compounds, heavy metals, pesticides or germs [5]. Mistakes in making them, where one herb is swapped for another, have also caused serious harm [5]. Testing and good manufacturing rules are the best protection.

Children and pregnancy

Few herbal products have been studied in children or in pregnancy. The NCCIH warns that supplements may be poor quality and contain drugs, chemicals or metals [9].

A checklist for buyers

  • Check the plant name and the part used, such as root or leaf.
  • Look for the amount of active ingredient per dose.
  • Prefer brands that publish independent test results.
  • Avoid products sold for weight loss, sex or bodybuilding with big promises [4].
  • Stop and seek care if you notice yellow skin, dark urine or severe stomach pain.

Who regulates herbal products?

Rules differ by country. In the US, the FDA does not review supplements for safety and effectiveness before they go on sale [3]. Buyers ordering online from abroad may get products made under weaker rules than at home.

WHO says member states' top request is for evidence, data, standards and rules for safe and fair use of traditional medicine [10].

  • Ashwagandha: some evidence for stress and insomnia; unclear for anxiety; rare liver injury [8].
  • Turmeric, ginger, ginseng: widely used; evidence differs by use and product.
  • Chinese herbal medicines: some products have been contaminated or mixed up [5].

Studies of one product do not always apply to another. The amount of active compound can differ a lot between brands, batches and plant parts.

Tell your health team

The NCCIH advises telling all health providers about any complementary products you use [3]. This helps them spot interactions and side effects. It matters most before surgery, during pregnancy, and for people taking several prescription medicines.

Using supplements wisely

The NCCIH notes that some supplements have shown some benefit, such as melatonin for jet lag. Others show little or no benefit, such as ginkgo for dementia [11]. Buyers should look for good research on the exact use they want, not general claims of "wellness".

Key numbers at a glance

  • 170 of 194 WHO member states report traditional medicine use.
  • 40–90% of people use it in those countries.
  • India backed WHO's Global Traditional Medicine Centre with US$250 million.
  • In the US, the FDA does not review supplements before sale.

Herbal products are popular worldwide. Trust depends on quality testing and honest claims.

Where to read more

All figures in this article come from public sources listed below. For more detail, start with the NCCIH pages on herbal supplements and herb-drug interactions, and WHO's traditional medicine pages. Each is free to read online.

What this means

Demand for herbal products is strong, especially in Asia. The brands that will last are the ones that test their products, publish evidence and make honest claims.

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Topics: Nutrition · OTC medicines

Sources

  1. WHO news (17 Dec 2025): Second Global Summit on traditional medicine
  2. WHO news (25 Mar 2022): WHO establishes the Global Centre for Traditional Medicine in India
  3. NCCIH: Dietary and herbal supplements
  4. NCCIH: 5 tips – what consumers need to know about dietary supplements
  5. NCCIH: Traditional Chinese medicine – what you need to know
  6. WHO news (25 Sep 2025): Traditional Medicine Global Library to launch in 2025
  7. NCCIH: Herb-drug interactions
  8. NCCIH: Ashwagandha – usefulness and safety
  9. NCCIH: 10 things to know about dietary supplements for children and teens
  10. WHO Global Traditional Medicine Centre: About us
  11. NCCIH: Using dietary supplements wisely

Banner image: Medicinal herbs garden hospital by User:Mattes, Public domain, via Wikimedia Commons.

Topics: Nutrition · OTC medicines

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