Sleep Drugs: Medicare Part D Spending

• 47medicines with Part D spending (calendar year 2024)

Each number has its full source under its own list below.

1. 1LokelmaSodium Zirconium Cyclosilicate · $26.66 per unit$239 million
2. 2XywavSodium,Calcium,Mag,Pot Oxybate · $37.03 per unit$210.5 million
3. 3Sodium OxybateSodium Oxybate · $33.90 per unit$78.6 million
4. 4XyremSodium Oxybate · $39.27 per unit$70.3 million
5. 5Doxepin HCl*Doxepin HCl · $0.92 per unit$65.7 million
6. 6Sod Sulf-Potass Sulf-Mag SulfSodium, Potassium,Mag Sulfates · $0.18 per unit$56.6 million
7. 7Zolpidem Tartrate*Zolpidem Tartrate · $0.18 per unit$50.1 million
8. 8Calcium AcetateCalcium Acetate · $0.30 per unit$27.6 million
9. 9ModafinilModafinil · $1.41 per unit$26.7 million
10. 10RamelteonRamelteon · $3.03 per unit$24.1 million
11. 11EszopicloneEszopiclone · $0.59 per unit$18.5 million
12. 12LumryzSodium Oxybate · $492.99 per unit$16.1 million
13. 13Sps*Sodium Polystyrene Sulfon/Sorb · $0.41 per unit$13.6 million
14. 14ProvigilModafinil · $72.95 per unit$13.2 million
15. 15Zolpidem Tartrate ERZolpidem Tartrate · $0.81 per unit$10.9 million

Source: Centers for Medicare & Medicaid Services, Medicare Part D Spending by Drug, calendar year 2024. Retrieved 12 Nov 2026.

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