Medical Devices US

US Liquid Biopsy Market Analysis, 2024–2034

US Liquid Biopsy Market Industry Trends and Forecast to 2034: Segmented by (Biomarker, Application, End User, Region) - Growth, Market Size, Future Prospects & Competitive Analysis, 2024-2034

Overview

Market Dashboard

US · 2024–2034 · estimates

Values shown here are estimates. Researched 2024 historical, 2025 base-year and 2026–2034 forecast values are prepared with the full report.

Estimate 2024 $3.38 Bn Estimated value
Estimate 2025 $3.88 Bn 43.6% of the global market
Projected 2034 $13.55 Bn 249% Adds $9.67 Bn over 9 forecast years
CAGR 2025–2034 14.9% Faster than 91% of 173 Medical Devices markets here
Key players 6 +1
  • US is 43.63% of the global market.
  • In North America, the largest is US (this report) at $3.88 Bn.
  • Fastest growing: Canada at 16.6% a year.
  • US ranks 1st of 2 by size in North America.

Market size projection

US

Source: Acuitas Health Analytics. Full methods, sources and usage terms come with report purchase.

Value added each year

$9.67 Bn total, 2026–2034

Year-by-year market size, 2024–2034
Liquid Biopsy Market market size by year, US
YearMarket sizeChange that yearSince 2025
2024 (estimate) $3.38 Bn — —
2025 (base) $3.88 Bn +$503.4 Mn —
2026 (forecast) $4.46 Bn +$578.4 Mn +14.9%
2027 (forecast) $5.13 Bn +$664.6 Mn +32%
2028 (forecast) $5.89 Bn +$763.6 Mn +51.7%
2029 (forecast) $6.77 Bn +$877.4 Mn +74.3%
2030 (forecast) $7.77 Bn +$1.01 Bn +100.3%
2031 (forecast) $8.93 Bn +$1.16 Bn +130.1%
2032 (forecast) $10.26 Bn +$1.33 Bn +164.4%
2033 (forecast) $11.79 Bn +$1.53 Bn +203.8%
2034 (forecast) $13.55 Bn +$1.76 Bn +249%

Estimates. Each year is projected from our earlier market estimate and its CAGR. Researched values come with the full report.

Same market worldwide

By geography

  1. Global $8.90 Bn
  2. North America $4.10 Bn
  3. US (this report) $3.88 Bn
  4. APAC $2.00 Bn
  5. Europe $1.60 Bn
  6. China $835.5 Mn
  7. Canada $632.6 Mn
  8. Japan $637.9 Mn
  9. Latin America $360.1 Mn
  10. Middle East $328.0 Mn
  11. Germany $271.7 Mn
  12. UK $252.8 Mn
  13. France $252.9 Mn
  14. Brazil $213.0 Mn
  15. Spain $189.9 Mn
  16. Ecuador $191.0 Mn
  17. Italy $182.5 Mn
  18. Saudi Arabia $170.5 Mn
  19. India $164.7 Mn
  20. Africa $128.9 Mn
  21. Mexico $116.6 Mn
  22. Russia $100.6 Mn
  23. Australia $99.4 Mn
  24. New Zealand $94.9 Mn
  25. South Africa $60.9 Mn
  26. UAE $48.1 Mn
  27. Egypt $23.2 Mn
  28. Philippines $21.3 Mn
  29. Hong Kong $14.2 Mn
  30. Malaysia $13.2 Mn
  31. Singapore $12.2 Mn
  32. Thailand $11.8 Mn
  33. Kenya $7.0 Mn

The US Liquid Biopsy Market Analysis Executive Summary

Liquid biopsy finds cancer signals such as tumour DNA in a blood sample, to detect cancer, guide treatment and check for relapse.

Key segments of the liquid Biopsy market include biomarker (Circulating Tumor DNA, Circulating Tumor Cells and Exosomes) and application (Treatment Selection, Recurrence Monitoring and Early Detection).

US Liquid Biopsy Market Dynamics

Market Growth Drivers

Rising cancer cases, earlier detection, precision medicine and a strong pipeline of targeted and immune therapies are driving the liquid Biopsy market. Faster approvals and new combinations are improving survival.

Opportunity

Biomarker-led treatment, earlier lines of therapy and expansion into emerging markets offer strong growth for the liquid Biopsy market.

Market Restraints

High treatment costs, drug resistance, side effects and unequal access to cancer centres hold back the liquid Biopsy market, especially in low- and middle-income countries.

Competitive Landscape for Liquid Biopsy Market in US

The liquid Biopsy market is moderately concentrated. Leading companies compete on product innovation, clinical evidence, pricing and geographic reach, and use partnerships and acquisitions to expand their portfolios.

Key Players

Healthcare Policies and Regulatory Landscape for Liquid Biopsy Market in US

Policy changes and Reimbursement scenario

Medical device rules, such as the US FDA 510(k) and PMA pathways and the EU Medical Device Regulation, govern how liquid Biopsy products are approved and monitored. Reimbursement codes and hospital purchasing policies decide how widely they are used in US.

Beyond the market numbers

Research, trials and patients

What doctors and scientists are doing in Liquid Biopsy right now, from free public sources.

Clinical trials

50 active trials in the US

Recruiting, about to start, or running now.

Top trial sponsors (worldwide)

  1. Epiliquid Holding, Inc 3 active trials on ClinicalTrials.gov (opens in a new tab)
  2. Gene Solutions 3 active trials on ClinicalTrials.gov (opens in a new tab)
  3. Tethis S.p.A. 2 active trials on ClinicalTrials.gov (opens in a new tab)
  4. Guardant Health, Inc. 2 active trials on ClinicalTrials.gov (opens in a new tab)

Source: ClinicalTrials.gov, Industry lead sponsors of active studies found with this market's trial search, worldwide. Retrieved 13 Nov 2026.

See every trial on ClinicalTrials.gov (opens in a new tab)

Latest research 10,752 papers since 2021 (worldwide)

  1. Deploying liquid intelligence in cancer: Finding answers in our blood. Cell, 2026
  2. Plasma ATR-FTIR spectroscopy combined with machine learning for early classification of response to neoadjuvant endocrine therapy: exploratory results from the ANNE trial. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2026
  3. APOBEC3-mediated therapy resistance and immunogenicity in solid tumors: from genomic scars to therapeutic vulnerabilities. ESMO open, 2026
  4. A noninvasive risk stratification prediction model for neuroblastoma through integration of multidimensional clinical indicators. European journal of pediatrics, 2026
  5. Recent Advancements in Diagnosis and Targeted Therapy of Pancreatic Cancer. Anti-cancer agents in medicinal chemistry, 2026
Search all of them on PubMed (opens in a new tab)

Sources: PubMed (US National Library of Medicine), ClinicalTrials.gov, World Bank. Fetched 12 Nov 2026. Papers and trials are found by search words, so the counts are a guide. Titles only; read each paper at its source.

Public data, with sources

Liquid Biopsy in context

The US compared

  • Health spending per person: 13,473 US$ per person (2023). World: 1,317 US$ per person (2023).[1]
  • Doctors: 3.68 per 1,000 people (2022). World: 1.86 per 1,000 people (2022).[2]
  • People aged 65 and over: 18.4% of people (2025). World: 10.4% of people (2025).[3]

Questions, answered with public data

How many clinical trials on Liquid Biopsy are running in the US?
50 studies are recruiting, active or about to start in the US.[4]
How much research is published on Liquid Biopsy?
PubMed lists 10,752 papers added since January 2021 that match this market, worldwide.[5]

[1] World Bank Open Data, Health spending per person (US$ per person). Retrieved 13 Nov 2026.

[2] World Bank Open Data, Doctors (per 1,000 people). Retrieved 13 Nov 2026.

[3] World Bank Open Data, People aged 65 and over (% of people). Retrieved 13 Nov 2026.

[4] ClinicalTrials.gov, Studies recruiting, active or not yet recruiting, in the US. Retrieved 12 Nov 2026.

[5] PubMed, Papers added since 1 January 2021 matching this market. Retrieved 12 Nov 2026.

Free data on this topic

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